lyprinol question

Question:

>I drink quite a lot of tea, and it just might help — when I miss it, >I feel a bit itchier.  

HI, JR. Tea makes me just as "spotty" as coffee; so you might want to consider going without. I’m not at all clear about what has caused me itching, in the past, but it is evidentally something I don’t eat much of these days or aply to my skin. I was told, years ago by a young derm. at U. of Oregon that psoriasis, by itself, does not itch, that itching is symptomatic of an allergy, which might be topical or dietary. >Which is not to preclude the idea that there might be an herb or >animal out there with just the right suppressor for at least a few >people’s psoriasis, plus or minus combination with others.  Ain’t >likely, perhaps, but we gotta do something to pass the time, right?

I’ve had some minor help from grapeseed extract and EPO, but the biggest bang for the buck has been from eliminating and reducing things in the diet. Best wishes, Terry — To send friendly e-mail, replace "nospam" with "ttowne1" and "emptymind" with "mindspring.

Response:

http://www.google.com/search?q=lyprinol&hl=en&safe=off&start=0&sa=N http://www.aomega.com/ahs/l1116b.htm Lyprinol (lyprinex).  Very interesting!  Omega-3’s from green mussel, otc, available all over, cheap, has a reasonable rationale, … I’d like to hear from someone using, might even give it a go myself! — Zileuton   Available in:Tablets Drug Class:Selective 5-lipoxygenase inhibitor Not available over-the-counter Not available as Generic  Brand Names   Zyflo   Side Effects   Serious Liver problems causing nausea, fatigue, lethargy, skin rash or itching, yellow discoloration of the eyes or skin, flu-like symptoms, urine that is darker than normal. Call your doctor immediately.    Common Headache, general pain, abdominal pain, nausea, indigestion, muscle soreness, weakness.    Less Common Joint pain, chest pain, inflammation of the tissues surrounding the eye (conjunctivitis), constipation, dizziness, fever, gas, insomnia or sleepiness, neck pain, nervousness, urinary tract infection, vomiting. Zileuton … hmm.  It’s a good question whether it would help psoriasis, but it sounds definitely hazardous.  Interesting, tho. J.

Response:

>Zileuton … hmm.  It’s a good question whether it would help >psoriasis, but it sounds definitely hazardous.  Interesting, tho.

Mahonia Aquifolia contains alkaloids which are lipoxegenase inhibitors.  Sold over-the-counter as "homeopathic" treatments (at 10% it’s not very dilute!), though, they don’t appear to be so great at combatting psoriasis.  Perhaps, as has been suggested, the dosage is too low (but then a higher dosage would mean higher risk of side-effects, and plants alkaloids are, after all, usually poisons created to deter ingestion by animals or insects).    http://members.aol.com/psorsite/docs/oregongrape.html – Dave W. http://members.aol.com/psorsite/

Response:

>Mahonia Aquifolia contains alkaloids which are lipoxegenase >inhibitors.

Seems like practically all fruits and vegetables contain *some* degree of cox and lox inhibitors, onions and black tea (quercetin), ginger, garlic, turmeric, anything with bioflavinoids, … Probably our metabolism has evolved this very complex immune system so it is hard to stop simply by eating common foods, the system adjusts and uses remaining pathways … which are very poorly researched even today. I drink quite a lot of tea, and it just might help — when I miss it, I feel a bit itchier.  I’ve tried the quercetin capsules, they probably help a bit more, but I think it may work too well and make me more susceptible to colds, and there’s a bit of a rebound when I stop taking it.  I tried chopping up a whole onion into whatever I cooked for dinner for a couple of weeks, and it was tasty enough, and might have helped a little, but was certainly no cure, either.  And I eat a lot of garlic just because, and ginger, too, but no cures, once again. Which is not to preclude the idea that there might be an herb or animal out there with just the right suppressor for at least a few people’s psoriasis, plus or minus combination with others.  Ain’t likely, perhaps, but we gotta do something to pass the time, right? J.

Response:

Hi, Does anyone have any experience with lyprinol for psoriasis treatment. Since it appears to be effective in preventing leukotriene production, it would seem to be potentially beneficial. Alternatively, does anyone have experience in using the new leukotriene inhibitors,  like zileuton (available as Zyflo for asthma in US), or zafirlukast (Accolate in US which affects receptors in lung so I don’t know if same receptors are in skin) or the even newer montelukast (Singulair), pranlukast or verlukast.   I don’t think these are generally available yet, but thought someone may know of some trials.  The Zyflo would seem to me to be the best shot.   Thought maybe there is someone out there with asthma and psoriasis and maybe they’ve seen something. Best Wishes, Marv

Response:

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