ref: Sunday Times

Question:

>Hello all.. >This is my first posting to this group, although i have been reading for some >time now. >Following the article in the Sunday Times I visited my local pharmacist to ask >about Dovobet, and was told that it is not out yet on the market, but then he >mentioned protopic/tacrolimus which he said is very effective in the treatment >of p, and it has only been out since the begining of April here in the U.K.  I >did some research on the internet but it was only mentioned for the treatment >of eczema.. has anyone tried it for p?

Hey Zeinnah You can search the ng archives at google for prior discussion on protopic or any other subject at http://www.pinch.com/skin Short answer is that yes it has been tried, it was originally thought to be pretty much ineffective for P but has subsequently shown to be more effective in some cases particularly in places where steroids are contra-indicated such as face and groin. As for Dovobet, I looked it up when you posted this. It’s just a combination of dovonex and steroid. Dovonex and steroid from separate prescriptions but used in combination have been shown to be more effective for many than either singly, so this makes sense as an approach. But there are some other options open to you -just get a prescription for both and use them together or get a prescription to have your pharmacy compound them together. You’re going to need to get a prescription for the Dovobet anyway. It should be on the market fairly soon I’d think anyway as marketing authorization was given in Feb 2002 per the UK medicines control site at Http:// www.mca.gov.uk Maybe some of the delay is that it’s a canadian company?? Anyway, definitely consider giving the combined dovonex (daivonex) and steroid therapy a try, probably before the tacrolimus IMO as I believe it’s got a better record for effectiveness. And I’d be more comfortable using them as separate Rxs used in combination than the premixed Dovobet anyway because you are supposed to pulse use on steroids to lower side effect risk, while daivonex needs to be used fairly continually to be effective. Kim The Psoriasis Newsgroup Resource FAQ can be found at               http://pfaq.cjb.net but will also be coming soon (twice a month) to a            newsgroup near you…

Response:

Hello all.. This is my first posting to this group, although i have been reading for some time now. Following the article in the Sunday Times I visited my local pharmacist to ask about Dovobet, and was told that it is not out yet on the market, but then he mentioned protopic/tacrolimus which he said is very effective in the treatment of p, and it has only been out since the begining of April here in the U.K.  I did some research on the internet but it was only mentioned for the treatment of eczema.. has anyone tried it for p? Thanks

Response:

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